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EBOLA:FAVIPIRAVIR.
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Favipiravir also known as T-705 is an experimental anti-viral drug with activity against many RNA VIRUSES. It, like some other experimental antiviraldrugs (T-1105 and T-1106), is a pyrazinecarboxamide derivative. Favipiravir is active against influenza viruses,West Nile virus,yellow fever virus,foot and mouth disease virus as well as other flaviviruses,arenaviruses,bunyaviruses and alphaviruses. The mechanism of its actions is thought to be related to the selective inhibition of viral RNa-dependent RNA polymerase. Favipiravir does not inhibit RNA of DNA synthesis in mammalian cells and is not toxic to them.
The advantage of using favipiravir in an Ebola outbreak is that it
has already been extensively tested for use as an anti-viral in human
trials for influenza. The drug is now in a U.S. final-stage trial for
treating influenza.
In addition, the drug is a pill, unlike the
cocktail of injected antibodies administered to two Americans who got
Ebola. This means it may be easier to use in rural locations with
limited medical infrastructure.
Photographer:EPA
Liberian nurses carry an Ebola victim from a house for burial in the Banjor Community.
On August 5, a spokeswoman for MediVector declined to
comment on the possibility of human use of the drug in Ebola, and
deferred questions on subject to the Department of Defense.
Civil service instigates investigation into leaked memo from Foreign Office about supposed comments made in February Scotland’s first minister, Nicola Sturgeon, with David Cameron in her office at the Scottish parliament earlier this year. Photograph: WPA Pool/Getty A civil service inquiry into a leaked memo which claimed that Nicola Sturgeon privately wanted to see David Cameron remain in power after the general election has been instigated following calls from the First Minister. Ms Sturgeon described the allegation as “100% untrue” and accused Whitehall of “dirty tricks”.
Born Oludotun Adebayo 25 August 1960 (age 54) Lagos , Nigeria Other names The Referee Occupation Radio broadcaster, Writer Oludotun Adebayo MBE (born 25 August 1960) is a British radio presenter, writer and publisher. Adebayo, who is Nigerian-born, is best known for his work on Up All Night on BBC Radio 5 Live , as well as the obituary programme Brief Lives .
ADVERTISEMEN BUHARI An anti-corruption group, Civil Society Network Against Corruption, has called on President Muhammadu Buhari to revoke the oil pipeline protection contract awarded to a company linked to a former Niger Delta militant, Mr. Government Ekpemupolo, also known as Tompolo.
